TY - JOUR
T1 - Cognitive function and quality of life after surgery for early breast cancer in North Jutland, Denmark
AU - Debess, Jeanne
AU - Riis, Jens Østergaard
AU - Pedersen, Lars
AU - Ewertz, Marianne
N1 - Funding Information:
This research was supported by Danish Cancer Society.
PY - 2009
Y1 - 2009
N2 - Objective. The aim of this study was to assess cognitive function, quality of life, and psychological distress after surgery for early breast cancer but before initiation of adjuvant treatment. Material and methods. We performed a population-based study in the county of North Jutland, Denmark, including 124 women aged less than 60 years who had surgery for early breast cancer from 2004-2006. They were compared with an aged-matched group of 224 women without previous cancer selected randomly from the same population. The cognitive function of patients and controls was tested using a revised battery from the ISPOCD study. Data were collected on quality of life (EORTC QLQ-C30) and psychological distress (POMS). Result. The neuropsychological tests did not reveal significant differences between patients and controls. Compared to the control group, breast cancer patients had a significantly 3 4 fold increased risk of experiencing cognitive impairment. Quality of life and psychological distress were also significantly poorer among patients. Conclusion. This study demonstrated that women diagnosed with breast cancer experience a significant deterioration of their perceived cognitive functioning, quality of life and of psychological well being.
AB - Objective. The aim of this study was to assess cognitive function, quality of life, and psychological distress after surgery for early breast cancer but before initiation of adjuvant treatment. Material and methods. We performed a population-based study in the county of North Jutland, Denmark, including 124 women aged less than 60 years who had surgery for early breast cancer from 2004-2006. They were compared with an aged-matched group of 224 women without previous cancer selected randomly from the same population. The cognitive function of patients and controls was tested using a revised battery from the ISPOCD study. Data were collected on quality of life (EORTC QLQ-C30) and psychological distress (POMS). Result. The neuropsychological tests did not reveal significant differences between patients and controls. Compared to the control group, breast cancer patients had a significantly 3 4 fold increased risk of experiencing cognitive impairment. Quality of life and psychological distress were also significantly poorer among patients. Conclusion. This study demonstrated that women diagnosed with breast cancer experience a significant deterioration of their perceived cognitive functioning, quality of life and of psychological well being.
UR - http://www.scopus.com/inward/record.url?scp=65549151251&partnerID=8YFLogxK
U2 - 10.1080/02841860802600755
DO - 10.1080/02841860802600755
M3 - Journal article
C2 - 19096948
AN - SCOPUS:65549151251
SN - 0284-186X
VL - 48
SP - 532
EP - 540
JO - Acta Oncologica
JF - Acta Oncologica
IS - 4
ER -