Music Therapy as Treatment of Negative Symptoms for Adult Patients Diagnosed with Schizophrenia: Study Protocol for a Randomized, Controlled and Blinded Study

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Abstract

Abstract:Background: Three Cochrane Reviews show that music therapy has a positive effect on schizophrenia concerning general functioning and positive/negative symptoms. This study aims at replicating these results in the Danish health system, a requirement for recommendation in guidelines from the Danish National Board of Health. Methods/Design: The study is a randomized, controlled study with a blinded design aiming at including 90 participants, 18 – 65 years diagnosed according to ICD-10 with a schizophrenia diagnosis. Participants are randomized to one of two different music therapy activities for 25 weekly sessions. The study interventions are added to standard care. Outcome measures are rated at baseline, after 15 sessions and post therapy. A qualitative interview is performed at one month follow up at end of study. The primary outcome is a reduction in negative symptoms. The secondary outcome is progression in quality of life, alliance and psychosocial functioning. Results: As this study is still running the results are not yet available. Conclusion: The study will investigate the direct effects of music therapy on negative symptoms as part of schizophrenia in a blinded, randomized trial. If proven effective, music therapy can be added to the small treatment armamentarium of effective therapies for negative symptoms.

Translated title of the contributionMusikterapi til behandling af skizofreniaptienters negative symptomer. Forskningsprotokol for et randomiseret, kontrlleret og blindet studie.
Original languageEnglish
JournalMedicines
Volume6
Issue number46
Pages (from-to)1-15
Number of pages15
DOIs
Publication statusPublished - 1 Apr 2019

Keywords

    Cite this

    @article{c8f2430df51d4cf28dae96b5ba6fec10,
    title = "Music Therapy as Treatment of Negative Symptoms for Adult Patients Diagnosed with Schizophrenia: Study Protocol for a Randomized, Controlled and Blinded Study",
    abstract = "Abstract:Background: Three Cochrane Reviews show that music therapy has a positive effect on schizophrenia concerning general functioning and positive/negative symptoms. This study aims at replicating these results in the Danish health system, a requirement for recommendation in guidelines from the Danish National Board of Health. Methods/Design: The study is a randomized, controlled study with a blinded design aiming at including 90 participants, 18 – 65 years diagnosed according to ICD-10 with a schizophrenia diagnosis. Participants are randomized to one of two different music therapy activities for 25 weekly sessions. The study interventions are added to standard care. Outcome measures are rated at baseline, after 15 sessions and post therapy. A qualitative interview is performed at one month follow up at end of study. The primary outcome is a reduction in negative symptoms. The secondary outcome is progression in quality of life, alliance and psychosocial functioning. Results: As this study is still running the results are not yet available. Conclusion: The study will investigate the direct effects of music therapy on negative symptoms as part of schizophrenia in a blinded, randomized trial. If proven effective, music therapy can be added to the small treatment armamentarium of effective therapies for negative symptoms.",
    keywords = "schizofreni; negative symptomer; isolation; musikterapi behandling",
    author = "Pedersen, {Inge Nygaard} and Bonde, {Lars Ole} and Niels Hannibal and Jimmi Nielsen and J{\o}rgen Aagaard and Bertelsen, {Lars Rye} and Jensen, {Silvia beatriz} and Nielsen, {Ren{\'e} Ernst}",
    year = "2019",
    month = "4",
    day = "1",
    doi = "10.3390/medicines6020046",
    language = "English",
    volume = "6",
    pages = "1--15",
    journal = "Medicines",
    issn = "2305-6320",
    publisher = "MDPI AG",
    number = "46",

    }

    TY - JOUR

    T1 - Music Therapy as Treatment of Negative Symptoms for Adult Patients Diagnosed with Schizophrenia

    T2 - Study Protocol for a Randomized, Controlled and Blinded Study

    AU - Pedersen, Inge Nygaard

    AU - Bonde, Lars Ole

    AU - Hannibal, Niels

    AU - Nielsen, Jimmi

    AU - Aagaard, Jørgen

    AU - Bertelsen, Lars Rye

    AU - Jensen, Silvia beatriz

    AU - Nielsen, René Ernst

    PY - 2019/4/1

    Y1 - 2019/4/1

    N2 - Abstract:Background: Three Cochrane Reviews show that music therapy has a positive effect on schizophrenia concerning general functioning and positive/negative symptoms. This study aims at replicating these results in the Danish health system, a requirement for recommendation in guidelines from the Danish National Board of Health. Methods/Design: The study is a randomized, controlled study with a blinded design aiming at including 90 participants, 18 – 65 years diagnosed according to ICD-10 with a schizophrenia diagnosis. Participants are randomized to one of two different music therapy activities for 25 weekly sessions. The study interventions are added to standard care. Outcome measures are rated at baseline, after 15 sessions and post therapy. A qualitative interview is performed at one month follow up at end of study. The primary outcome is a reduction in negative symptoms. The secondary outcome is progression in quality of life, alliance and psychosocial functioning. Results: As this study is still running the results are not yet available. Conclusion: The study will investigate the direct effects of music therapy on negative symptoms as part of schizophrenia in a blinded, randomized trial. If proven effective, music therapy can be added to the small treatment armamentarium of effective therapies for negative symptoms.

    AB - Abstract:Background: Three Cochrane Reviews show that music therapy has a positive effect on schizophrenia concerning general functioning and positive/negative symptoms. This study aims at replicating these results in the Danish health system, a requirement for recommendation in guidelines from the Danish National Board of Health. Methods/Design: The study is a randomized, controlled study with a blinded design aiming at including 90 participants, 18 – 65 years diagnosed according to ICD-10 with a schizophrenia diagnosis. Participants are randomized to one of two different music therapy activities for 25 weekly sessions. The study interventions are added to standard care. Outcome measures are rated at baseline, after 15 sessions and post therapy. A qualitative interview is performed at one month follow up at end of study. The primary outcome is a reduction in negative symptoms. The secondary outcome is progression in quality of life, alliance and psychosocial functioning. Results: As this study is still running the results are not yet available. Conclusion: The study will investigate the direct effects of music therapy on negative symptoms as part of schizophrenia in a blinded, randomized trial. If proven effective, music therapy can be added to the small treatment armamentarium of effective therapies for negative symptoms.

    KW - schizofreni; negative symptomer; isolation; musikterapi behandling

    U2 - 10.3390/medicines6020046

    DO - 10.3390/medicines6020046

    M3 - Journal article

    VL - 6

    SP - 1

    EP - 15

    JO - Medicines

    JF - Medicines

    SN - 2305-6320

    IS - 46

    ER -