TY - JOUR
T1 - Pain Science in Practice (Part 3)
T2 - Peripheral Sensitization.
AU - Hoegh, Morten
PY - 2022/6
Y1 - 2022/6
N2 - In most cases, tissue injuries lead to inflammation and sensitization. From a neuroscience perspective, this is why one usually hurts when one is injured. Peripheral sensitization is an essential principle in pain science, and it is associated with hyperalgesia, inflammation, and clinical pain conditions, including acute injuries and rheumatological diseases. This editorial explains peripheral sensitization, neurogenic inflammation, and the axon reflex, as well as the role of second messengers and peptidergic C-fibers.
AB - In most cases, tissue injuries lead to inflammation and sensitization. From a neuroscience perspective, this is why one usually hurts when one is injured. Peripheral sensitization is an essential principle in pain science, and it is associated with hyperalgesia, inflammation, and clinical pain conditions, including acute injuries and rheumatological diseases. This editorial explains peripheral sensitization, neurogenic inflammation, and the axon reflex, as well as the role of second messengers and peptidergic C-fibers.
KW - musculoskeletal pain
KW - neuroscience
KW - pain
KW - pain education
UR - http://www.scopus.com/inward/record.url?scp=85131270409&partnerID=8YFLogxK
U2 - 10.2519/jospt.2022.11202
DO - 10.2519/jospt.2022.11202
M3 - Editorial
C2 - 35647877
SN - 0190-6011
VL - 52
SP - 303
EP - 306
JO - Journal of Orthopaedic and Sports Physical Therapy
JF - Journal of Orthopaedic and Sports Physical Therapy
IS - 6
ER -