Foto af Annette Burkhart Larsen

Annette Burkhart Larsen

Kandidat i Medicin med Industriel Specialisering - Biomedicin

  • Fredrik Bajers Vej 7, D, D2-111

    9220 Aalborg Ø

    Danmark

20112019
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Publikationer 2011 2019

2019
Hepcidins
Ficus
PC12 Cells
Iron
Messenger RNA
1 Citation (Scopus)
Hepcidins
PC12 Cells
Iron
Messenger RNA
Deferoxamine
6 Citationer (Scopus)

Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo

Johnsen, K. B., Bak, M., Melander, F., Thomsen, M. S., Burkhart, A., Kempen, P. J., Andresen, T. L. & Moos, T., 10 feb. 2019, I : Journal of Controlled Release. 295, s. 237-249 13 s.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Transferrin Receptors
Blood-Brain Barrier
Gold
Nanoparticles
Antibodies
2018
8 Citationer (Scopus)
525 Downloads (Pure)

Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles

Johnsen, K. B., Bak, M., Kempen, P. J., Melander, F., Burkhart, A., Thomsen, M. S., Nielsen, M. S., Moos, T. & Andresen, T. L., 2018, I : Theranostics. 8, 12, s. 3416-3436

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Transferrin Receptors
Antibody Affinity
Gold
Nanoparticles
Nanomedicine
2017
13 Citationer (Scopus)
Endothelial cells
Pericytes
Blood-Brain Barrier
Basement Membrane
Brain
32 Citationer (Scopus)
31 Downloads (Pure)

Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

Johnsen, K. B., Burkhart, A., Melander, F., Kempen, P. J., Vejlebo, J. B., Siupka, P., Nielsen, M. S., Andresen, T. L. & Moos, T., 1 dec. 2017, I : Scientific Reports. 7, 13 s., 10396.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Transferrin Receptors
Blood-Brain Barrier
Brain
Endothelium
Transcytosis
1 Citation (Scopus)
Erythropoietin
Transfection
Endothelial Cells
Brain
Proteins
2016

A triple co-culture model of the blood-brain barrier using primary porcine brain endothelial cells, porcine pericytes and porcine astrocytes

Thomsen, L. B., Larsen, A. B. & Moos, T., 2016, IPC nr. C12N 5/071 (2010.01), C12N 5/079 (2010.01), G01N 33/50 (2006.01), Patentnr. WO/2016/202343 , 22 dec. 2016, Prioritetsdato 16 jun. 2016, Prioritetsnr. PCT/DK2016/050190

Publikation: PatentForskning

Åben adgang

Expression and deposition of basement membrane proteins by brain capillary endothelial cells in a primary murine model of the blood-brain barrier

Thomsen, M. S., Birkelund, S., Larsen, A. B., Stensballe, A. & Moos, T., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, s. 37 P-12

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

22 Citationer (Scopus)

Expression of iron-related proteins at the neurovascular unit supports reduction and reoxidation of iron for transport through the blood-brain barrier

Burkhart, A., Skjørringe, T., Johnsen, K. B., Siupka, P., Thomsen, L. B., Nielsen, M. S., Thomsen, L. L. & Moos, T., 2016, I : Molecular Neurobiology. 53, 10, s. 7237-7253

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Blood-Brain Barrier
Iron
Ceruloplasmin
Brain
Endothelial Cells

Gene delivery of the therapeutic polypeptide erythropoietin to primary brain capillary endothelial cells for protein secretion

Larsen, A. B. & Moos, T., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, s. 25 O-5

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood-brain barrier

Moos, T., Routhe, L. J., Birkelund, S., Burkhart, A., Stensballe, A. & Thomsen, M. S., 2016, 46th Annual Meeting of the Society for Neuroscience, Neuroscience 2016, 12-16 November 2016, San Diego, CA, USA. Society for Neuroscience, 140.10 / U1

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

Åben adgang

Targeting immunoliposomes to transferrin receptors on brain capillary endothelial cells as a mean for cargo transport across the blood-brain barrier

Moos, T., Johnsen, K. B., Burkhart, A., Bruun, J., Siupka, P., Nielsen, M. S. & Andresen, T., 2016, 46th Annual Meeting of the Society for Neuroscience, Neuroscience 2016, 12-16 November 2016, San Diego, CA, USA. Society for Neuroscience, 140.13 / U4

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

Åben adgang

Targeting immunoliposomes to transferrin receptors on brain capillary endothelial cells as a mean for cargo transport across the blood-brain barrier

Johnsen, K. B., Larsen, A. B., Bruun, J., Siupka, P., Nielsen, M. S., Andresen, T. L. & Moos, T., 2016, Final Programme, 19th International Symposium on Signal Transduction at the Blood-Brain Barriers, 14-16 September 2016, Copenhagen, Denmark. University of Copenhagen, s. 51 P-51

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskningpeer review

2015
48 Citationer (Scopus)
197 Downloads (Pure)

A triple culture model of the blood-brain barrier using porcine brain endothelial cells, astrocytes and pericytes

Thomsen, L. B., Burkhart, A. & Moos, T., 2015, I : PLOS ONE. 10, 8, 16 s., e0134765.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Pericytes
blood-brain barrier
astrocytes
Endothelial cells
Blood-Brain Barrier
47 Citationer (Scopus)
187 Downloads (Pure)
Åben adgang
Fil
19 Citationer (Scopus)
228 Downloads (Pure)

Transfection of brain capillary endothelial cells in primary culture with defined blood-brain barrier properties

Larsen, A. B., Thomsen, L. B., Thomsen, M. S., Lichota, J., Fazakas, C., Krizbai, I. & Moos, T., 2015, I : Fluids and Barriers of the CNS. 12, 1, 14 s., 19.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Åben adgang
Fil
Blood-Brain Barrier
Transfection
Endothelial Cells
Brain
Astrocytes
2014
7 Citationer (Scopus)

Accessing targeted nanoparticles to the brain: the vascular route

Burkhart, A., Azizi, M., Thomsen, M. S., Thomsen, L. B. & Moos, T., 2014, I : Current Medicinal Chemistry. 21, 36, s. 4092-4099

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Ceruloplasmin is expressed by brain pericytes

Moos, T. & Larsen, A. B., 2014, Annual Meeting of the Society for Neuroscience, Neuroscience 2014, 15-19 November 2014, Washington, DC, USA. s. Poster No. 739.01/QQ4

Publikation: Bidrag til bog/antologi/rapport/konference proceedingKonferenceabstrakt i proceedingForskning

Gene delivery of therapeutic polypeptides to brain capillary endothelial cells for protein secretion

Larsen, A. B., Thomsen, L. B. & Moos, T., 2014.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Iron uptake and transport at the blood-brain barrier

Larsen, A. B., Thomsen, L. B. & Moos, T., 2014.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Blood-Brain Barrier
Iron
Gene Expression
Brain
Endothelial Cells

Transfection of rat brain endothelium in a primary culture model of the blood-brain barrier at different states of barrier maturity

Larsen, A. B., Thomsen, L. B., Lichota, J. & Moos, T., 2013.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

2012

Gene delivery into primary brain capillary endothelial cells for protein secretion: a novel strategy for drug delivery to the brain

Larsen, A. B., Thomsen, L. B., Lichota, J. & Moos, T., 2012.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Endothelial Cells
Brain
Blood-Brain Barrier
Pharmaceutical Preparations
Genes
2011

Gene delivery of therapeutic polypeptides into brain capillary endothelial cells for protein secretion

Moos, T., Larsen, A. B., Thomsen, L. B. & Lichota, J., 2011.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Gene delivery of therapeutic polypeptides into brain capillary endothelial cells for protein secretion

Larsen, A. B., Thomsen, L. B., Moos, T. & Lichota, J., 2011.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review