Projekter pr. år
Organisationsprofil
Head of research group:
Who we are?
Members of the group are genome researchers, computational and molecular biologists with expertise in human genetics and genomics, biobanking, genome-wide association studies, sequencing, transcriptomics, polygenic risk scores, risk prediction and biomarkers.
Our research – what we do?
Use genetics to systematically understand the biological basis of common complex diseases and identify biological subtypes of disease. We have focus on women's reproductive health, in particular endometriosis, cardiometabolic diseases and brain disorders. We work in the interface between wet-lab and big data analysis. Our goal is to turn genetic findings into personalised medicine and benefits patients.
How does our research contribute to societal health challenges?
Despite a high prevalence and socio-economic burden, women’s reproductive disorders remain underfunded and consequently under-researched. Many disorders, such as endometriosis and repeated pregnancy loss affects women during the prime years of their lives, causing problems for the women and their families as well as loss of productivity for the society. By developing molecular predictors and decision support tools within women's health our research contributes to increased equity in health and society.
Who are our key collaborators?
National and International research institutions
- Aarhus University
- Aarhus University Hospital
- Copenhagen University
- Technical University of Denmark
- Hvidovre Hospital
- University of Southern Denmark
- University of San Francisco, Oxford Big Data Institute
- University of Calgary
- University College London
- Oxford University.
Consortia and cohorts
- Danish Blood Donor Genomic Consortium (co-PI)
- Copenhagen Hospital Biobank (CHB)
- UK Biobank
- Biobank Rare Variant Analysis (BRaVa) consortium (Danish co-PI)
- Nordic Consortium of Womens Reproductive Health (NCWRH) (co-chair)
- International Endometriosis Genome Consortium (IEGC) (Danish PI)
- The Dan-NICAD (Danish Study of Non-Invasive Diagnostic Testing in Coronary Artery Disease) group
Industry
- PrecisionLife
- deCODE genetics
- Novo Nordisk
Fingerprint
Netværk
Profiler
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Steffan Noe Christiansen
- Det Sundhedsvidenskabelige Fakultet - Postdoc
- Institut for Medicin og Sundhedsteknologi - Postdoc
- Genomic Medicine - Postdoc
Person: VIP
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Faezeh Darki
- Det Sundhedsvidenskabelige Fakultet - Ph.d.-stipendiat
- Institut for Medicin og Sundhedsteknologi - Ph.d.-stipendiat
- Genomic Medicine - Ph.d.-stipendiat
Person: VIP
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Lisette Johanna Antonia Rodian Kogelman
- Det Sundhedsvidenskabelige Fakultet - Lektor
- Institut for Medicin og Sundhedsteknologi - Lektor
- Genomic Medicine - Lektor
Person: VIP
Projekter
- 5 Igangværende
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SURVIVE Unravelling endocrine mechanisms to improve maternal health and increase fetal survival
01/01/2023 → 31/12/2026
Projekter: Projekt › Forskning
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Integration of the Drosophila melanogaster Microbiome and Transcriptome for Enhanced Prediction of Late-Life Events
Kristensen, T. N., Rohde, P. D., Nielsen, K. L. & Lund Nielsen, J.
01/09/2022 → 31/08/2026
Projekter: Projekt › Forskning
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Functional Genomics in Endometriosis
Darki, F., Nyegaard, M. & Qvist, P.
01/07/2022 → 30/06/2025
Projekter: Projekt › Ph.d.-projekt
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Association between socioeconomic position and coronary artery calcium score in patients with symptoms suggestive of obstructive coronary artery disease
Nissen, L., Winding, T. N., Schmidt, S. E., Hasan Shafi, B., Bossano Prescott, E. I., Nyegaard, M., Winther, S. & Bøttcher, M., 14 feb. 2023, (E-pub ahead of print) I: Journal of Cardiovascular Computed Tomography.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Cell-free fetal DNA for genetic evaluation in Copenhagen Pregnancy Loss Study (COPL): a prospective cohort study
Schlaikjær Hartwig, T., Ambye, L., Gruhn, J. R., Petersen, J. F., Wrønding, T., Amato, L., Chi-Ho Chan, A., Ji, B., Bro-Jørgensen, M. H., Werge, L., Petersen, M. M. B. S., Brinkmann, C., Petersen, J. B., Dunø, M., Bache, I., Herrgård, M. J., Jørgensen, F. S., Hoffmann, E. R., Nielsen, H. S., COPL consortium, & 1 flere , 1 feb. 2023, (E-pub ahead of print) I: Lancet. 401, 10378, s. 762-771 10 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Danish translation, cross-cultural adaptation, and electronic migration of the World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project Endometriosis Patient Questionnaire
Thomsen, L. H., Vexø, L. E., Schnack, T. H., Hansen, K. E., Forman, A., Hartwell, D., Nielsen, H. S., Hummelshøj, L., Nyegaard, M. & Madsen, M. E., 13 mar. 2023, I: Frontiers in Global Women's Health. 4, 10 s., 1102006.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil4 Downloads (Pure)
Forskningsdatasæt
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Supplementary Material for Rohde et al., 2019
Rohde, P. D. (Ophavsperson), Jensen, I. R. (Ophavsperson), Sarup, P. M. (Ophavsperson), Ørsted, M. (Ophavsperson), Demontis, D. (Ophavsperson), Sørensen, P. (Ophavsperson) & Kristensen, T. N. (Ophavsperson), GSA Journals, 2019
DOI: 10.25386/genetics.9368636.v4, https://doi.org/10.25386%2Fgenetics.9368636.v4
Datasæt
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Supplementary Material for Rohde et al., 2019
Rohde, P. D. (Ophavsperson), Jensen, I. R. (Ophavsperson), Sarup, P. M. (Ophavsperson), Ørsted, M. (Ophavsperson), Demontis, D. (Ophavsperson), Sørensen, P. (Ophavsperson) & Kristensen, T. N. (Ophavsperson), GSA Journals, 2019
DOI: 10.25386/genetics.9368636.v1, https://gsajournals.figshare.com/articles/Supplementary_Material_for_Rohde_et_al_2019/9368636/1
Datasæt
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Supplementary Material for Rohde et al., 2019
Rohde, P. D. (Ophavsperson), Jensen, I. R. (Ophavsperson), Sarup, P. M. (Ophavsperson), Ørsted, M. (Ophavsperson), Demontis, D. (Ophavsperson), Sørensen, P. (Ophavsperson) & Kristensen, T. N. (Ophavsperson), GSA Journals, 2019
DOI: 10.25386/genetics.9368636.v2, https://gsajournals.figshare.com/articles/Supplementary_Material_for_Rohde_et_al_2019/9368636/2
Datasæt
Aktiviteter
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Prediction of high-risk plaques in coronary heart disease using genetics and targeted proteomics
Palle Duun Rohde (Foredragsholder)
3 nov. 2022Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
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Medlem af bedømmelsesudvalg PhD Anne Krogh Nøhr (Begivenhed)
Mette Nyegaard (Forperson)
1 jul. 2022Aktivitet: Medlemskab › Medlemskab af bedømmelsesudvalg
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Genetic superheroes carry key information to prevention of cardiovascular disease
Mette Nyegaard (Foredragsholder)
4 jun. 2022Aktivitet: Foredrag og mundtlige bidrag › Foredrag og præsentationer i privat eller offentlig virksomhed
Presse/medier
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Why proteins matter: the building blocks of who we are
Malene Bredal Brohus, Michael Toft Overgaard & Mette Nyegaard
15/02/2023
1 element af Mediedækning
Presse/medie
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Nordjyske forskere krydsforhørt i sag om den værste massemorder i Australiens historie
Mette Nyegaard & Michael Toft Overgaard
13/02/2023 → 14/02/2023
15 elementer af Mediedækning
Presse/medie
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Impacts
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Forskning i genfejl kan benåde australsk kvinde
Helene Halkjær Jensen (Deltager), Malene Bredal Brohus (Deltager), Michael Toft Overgaard (Deltager) & Mette Nyegaard (Deltager)
Impact: Social impact