Projekter pr. år
Organisationsprofil
Organisationsprofil
Head of research group:
Research group name
Genomic Medicine
Initials of research group
GM
Who we are?
The group members have a background in molecular medicine, computational biology, quantitative and statistical genetics with expertise within complex trait genetics, mathematical modelling, biostatistics, and machine learning.
Our research – what we do?
The Genomic Medicine research group is dedicated to leveraging large-scale genetics and genomics to investigate the phenotypic diversity in humans. Our mission focuses on pioneering the development of statistical genetic methods, implement machine learning algorithms, and integrate artificial intelligence to propel genetic research and precision medicine forward. We strive to create precision medicine tools and uncover novel causal mechanisms for multifactorial diseases.
How does our research contribute to societal health challenges?
By identifying the genetic causes, underlying molecular mechanisms, and developing molecular predictors and clinical decision support tools, our research contributes to increased equity in health and society.
FN's verdensmål
I 2015 blev FN-landene enige om 17 verdensmål til at standse fattigdom, beskytte planeten og sikre velstand for alle. Vores arbejde bidrager til følgende verdensmål:
Fingerprint
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Samarbejde i de sidste fem år
Klik på punkterne for at se detaljerne.
Profiler
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The Deadly, the Deleterious, and the Dangerous – Decoding the Differential Pathogenicity among CALM1, CALM2, and CALM3
Christiansen, S. N. N. (PI (principal investigator)), Nyegaard, M. (CoI (co-investigator)), Overgaard, M. T. (Andet), Schierup, M. H. (Andet), Tfelt-Hansen, J. (CoPI) & Schwartz, P. J. (Andet)
01/07/2024 → 30/06/2026
Projekter: Projekt › Forskning
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SURVIVE Unravelling endocrine mechanisms to improve maternal health and increase fetal survival
Rohde, P. D. (Projektdeltager) & Nyegaard, M. (CoI (co-investigator))
01/01/2023 → 31/12/2026
Projekter: Projekt › Forskning
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Integration of the Drosophila melanogaster Microbiome and Transcriptome for Enhanced Prediction of Late-Life Events
Kristensen, T. N. (PI (principal investigator)), Rohde, P. D. (CoI (co-investigator)), Nielsen, K. L. (CoI (co-investigator)) & Lund Nielsen, J. (CoI (co-investigator))
Danmarks Frie Forskningsfond | Natur og Univers
01/09/2022 → 31/08/2026
Projekter: Projekt › Forskning
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A genome-wide association meta-analysis links hidradenitis suppurativa to common and rare sequence variants causing disruption of the Notch and Wnt/β-catenin signaling pathways
Andersen, R. K., Stefansdottir, L., Riis, P. T., Halldorsson, G., Ferkingstad, E., Oddsson, A., Walters, G. B., Olafsdottir, T. A., Rutsdottir, G., Zachariae, C., Thomsen, S. F., Brodersen, T., Dinh, K. M., Knowlton, K. U., Knight, S., Nadauld, L. D., Banasik, K., Brunak, S., Hansen, T. F. & Hjalgrim, H. & 23 flere, , apr. 2025, I: Journal of the American Academy of Dermatology. 92, 4, s. 761-772 12 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil1 Citationer (Scopus)19 Downloads (Pure) -
Associations between past infectious mononucleosis diagnosis and 47 inflammatory and vascular stress biomarkers
Kristjánsson, R. P., Dietz, J.B.-N., Davíðsson, Ó. B., Kjerulff, B., Rostgaard, K., Dowsett, J., Søegaard, S. H., Rotbain, E. C., Schwinn, M., Burgdorf, K. S., Bay, J. T., Mikkelsen, C., Ullum, H., Brunak, S., Sørensen, E., Jensen, B. A., Bruun, M. T., Nyegaard, M., Ostrowski, S. R. & Pedersen, O. B. & 3 flere, , 2 apr. 2025, I: Scientific Reports. 15, 1, 11312.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
Åben adgangFil8 Downloads (Pure) -
Bayes PoPS: A Novel Bayesian Approach for Improved Polygenic Gene Prioritization
Rohde, P. D. & Sørensen, P., 25 maj 2025.Publikation: Konferencebidrag uden forlag/tidsskrift › Poster › Forskning
Fil
Forskningsdatasæt
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Additional file 2 of Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease
Møller, P. L. (Ophavsperson), Rohde, P. D. (Ophavsperson), Dahl, J. N. (Ophavsperson), Rasmussen, L. D. (Ophavsperson), Nissen, L. (Ophavsperson), Schmidt, S. E. (Ophavsperson), McGilligan, V. (Ophavsperson), Gudbjartsson, D. F. (Ophavsperson), Stefansson, K. (Ophavsperson), Holm, H. (Ophavsperson), Bentzon, J. F. (Ophavsperson), Bøttcher, M. (Ophavsperson), Winther, S. (Ophavsperson) & Nyegaard, M. (Ophavsperson), Figshare, 15 aug. 2024
DOI: 10.6084/m9.figshare.25449091.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Predicting_the_presence_of_coronary_plaques_featuring_high-risk_characteristics_using_polygenic_risk_scores_and_targeted_proteomics_in_patients_with_suspected_coronary_artery_disease/25449091/1
Datasæt
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Additional file 2 of Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease
Møller, P. L. (Ophavsperson), Rohde, P. D. (Ophavsperson), Dahl, J. N. (Ophavsperson), Rasmussen, L. D. (Ophavsperson), Nissen, L. (Ophavsperson), Schmidt, S. E. (Ophavsperson), McGilligan, V. (Ophavsperson), Gudbjartsson, D. F. (Ophavsperson), Stefansson, K. (Ophavsperson), Holm, H. (Ophavsperson), Bentzon, J. F. (Ophavsperson), Bøttcher, M. (Ophavsperson), Winther, S. (Ophavsperson) & Nyegaard, M. (Ophavsperson), Figshare, 15 aug. 2024
DOI: 10.6084/m9.figshare.25449091, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Predicting_the_presence_of_coronary_plaques_featuring_high-risk_characteristics_using_polygenic_risk_scores_and_targeted_proteomics_in_patients_with_suspected_coronary_artery_disease/25449091
Datasæt
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Data from: The Drosophila Genetic Reference Panel (DGRP) on locomotor activity across different environmental conditions
Krog Noe, N. (Ophavsperson), Duun Rohde, P. (Ophavsperson), Sørensen, P. (Ophavsperson) & Nygaard Kristensen, T. (Ophavsperson), Dryad, 14 feb. 2024
DOI: 10.5061/dryad.fxpnvx10n, https://datadryad.org/dataset/doi:10.5061/dryad.fxpnvx10n
Datasæt
Aktiviteter
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Prediction of high-risk plaques in coronary heart disease using genetics and targeted proteomics
Rohde, P. D. (Foredragsholder)
3 nov. 2022Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
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Medlem af bedømmelsesudvalg PhD Anne Krogh Nøhr (Begivenhed)
Nyegaard, M. (Forperson)
1 jul. 2022Aktivitet: Medlemskab › Medlemskab af bedømmelsesudvalg
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Genetic superheroes carry key information to prevention of cardiovascular disease
Nyegaard, M. (Foredragsholder)
4 jun. 2022Aktivitet: Foredrag og mundtlige bidrag › Foredrag og præsentationer i privat eller offentlig virksomhed
Presse/medier
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Debat: Danmark skal have et nationalt videnscenter for kvinders sundhed
27/06/2025
1 element af Mediedækning
Presse/medie
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Tusinder rammes af uforklarlige graviditetstab. Nu udfordrer forskere årsagen
06/06/2025 → 09/06/2025
2 elementer af Mediedækning
Presse/medie
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Debat: Danmark skal have et nationalt videnscenter for kvinders sundhed
04/06/2025
1 element af Mediedækning
Presse/medie
Impacts
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Forskning i genfejl kan benåde australsk kvinde
Jensen, H. H. (Deltager), Brohus, M. B. (Deltager), Overgaard, M. T. (Deltager) & Nyegaard, M. (Deltager)
Impact: Social impact